Is It Possible to Overdose on Cannabis?

Almost every drug used as medicine is given a so called LD – 50. This LD – 50 rating shows us the dosage at which 50 per cent of test animals that are given a certain drug will die due to intoxication of that very drug. Now let’s consider cannabis.


Is this possible with cannabis? Can one induce death in test animals with marijuana? The answer is very simple: No, you can’t! Researchers in the past have attempted to determine the LD – 50 rating of marijuana in test animals with no success.

Marijuana is considered remarkably safe because of the lack of overdose risk, and at this moment its LD – 50 rating is estimated at around 1:20 000 or 1:40 000. Or if we keep it simple, in order to overdose on cannabis one must consume 20 000 or 40 000 times as much as one average marijuana cigarette. This means, theoretically, that a person must consume almost 1500 pounds of marijuana in a period of fifteen minutes to induce a lethal response.

Consuming concentrates or ‘dabs’, which are 3-4 times more potent than their flower equivalent, can be more dangerous but still impossible to cause overdose and death. Simply because it still takes hundreds of pounds of ‘dabs’ to be consumed within 15 minutes to have a lethal reaction. In every scenario, a person would pass out before experiencing fatal consequences.emergency_cannabis_overdose

It is impossible to overdose on marijuana! This statement, as such, is supported and explained by the Nacional Cancer Institute:

“Because cannabinoid receptors, unlike opioid receptors, are not located in the brainstem areas controlling respiration, lethal overdoses from Cannabis and cannabinoids do not occur.”


Or, in other words, unlike other drugs, taking too much marijuana will not cost you your life!

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