What are cannabinoids, the relationship between cannabinoids and the body.
The chemically active compounds uniquely found in Cannabis sativa L are called cannabinoids.
So far at least 85 cannabinoids have been identified in cannabis, most of which serve medical purposes, and are the main cause why medicinal cannabis relieves number of symptoms, such as pain and nausea.
Different kinds of cannabinoids imitate and stimulate endocannabinoids (compounds produced naturally in our own bodies – named after the plant Cannabis sativa), or simply said, they are the reason cells communicate, and insufficiency and complications in our endocannabinoid system occur our body can’t maintain health and internal stability.
The way cannabinoids work is that they bind themselves and interact with different receptors, which are located in the immune or nervous system. There are two types of receptors that cannabinoids activate, and that is the reason why different cannabinoids cause different effects. CB-1 receptors, found in the brain and the nerve endings, or generally in the nervous system. These are receptors to which the cannabinoid THC (tetrahydrocannabinol) binds. The second type of receptors activated by cannabinoids are called CB-2 receptors, located throughout the body within the immune system, usually activated by the cannabinoid – CBN (cannabinol).
Using the appropriate cannabinoids to activate the right receptors is the foundation of the medical marijuana treatment.
THC, CBD, CBN and CBG – The most common types of cannabinoids
THC (Tetrahydrocannabinol) – the most frequent psychoactive cannabinoid was discovered in 1964 by Dr. Raphael Mechoulam. THC has a number of medical benefits, such as pain relief, treating nausea and vomiting, and asthma. Although THC is still illegal in most countries in the world, its synthetic versions are being recommended on a daily basis.
CBD (Cannabidiol) is the second most common cannabinoid. It is famous for its non-psychoactive effect, relieving pain, and also calming the nervous system. Newest researches suggest that this cannabinoid helps people who suffer from epilepsy, schizophrenia and other diseases.
CBN (Cannabinol) is a cannabinoid created with the process of oxidation of THC. It is lightly psychoactive, and when mixed with THC, CBD can induce sleep.
CBG (Cannabigerol) – Cannabinoid with no psychoactive effects, most famous because it can reduce the fluid pressure inside the eye (IOP) which makes it perfect for patients suffering glaucoma.